Registered Data
Contents
- 1 [CT183]
- 1.1 [02625] Topology-Driven Shape Programmability in Tissue Morphogenesid
- 1.2 [01173] Turing Patterns as a Model for Brain Folding
- 1.3 [01299] Mathematical modelling of peristaltic driven two-layered catheterized oesophagus
- 1.4 [00659] Understanding persisting onchocerciasis hotspots in Africa using mathematical models
- 1.5 [00709] Mathematical modeling reveals P2X1 purinoceptor antagonist as a male contraceptive
[CT183]
- Session Time & Room
- Classification
[02625] Topology-Driven Shape Programmability in Tissue Morphogenesid
- Session Time & Room : 5D (Aug.25, 15:30-17:10) @D514
- Type : Contributed Talk
- Abstract : The ability of a pre-patterned and subsequently activated spontaneous strain field to drive shape transformations has gained increasing appreciation in device design, engineering, and the physics of metric shape-programmability. Many of these ideas may also hold relevance for understanding tissue morphogenesis. We show spatiotemporal patterns of active cell behaviours can be coarse-grained to yield similar spontaneous strain fields, and how topological defects in these fields can organise shape outcomes and provide robustness against natural variability.
- Classification : 92C05, 92C15, 74M05, 92-10, 92-08
- Format : Talk at Waseda University
- Author(s) :
- Carl D Modes (Max Planck Institute of Molecular Cell Biology and Genetics)
[01173] Turing Patterns as a Model for Brain Folding
- Session Time & Room : 5D (Aug.25, 15:30-17:10) @D514
- Type : Contributed Talk
- Abstract : Folding patterns of every human brain are unique with no consensus among neurobiologists regarding the mechanism for folding pattern formation. We present a Turing reaction-diffusion model that uses an activator and inhibitor, and incorporates parameters that influence genetic control, brain growth, and domain scale. Our results study static and dynamic domain growth, and we investigate domain shape to compare results to brain diseases with excessive folding or lack of folding such as polymicrogyria and lissencephaly.
- Classification : 92C15, 92B05, 92-10, 37N25, 35B36, Turing Pattern Formation, Brain Development, PDEs, Modeling, Dynamical Systems
- Format : Talk at Waseda University
- Author(s) :
- Monica K. Hurdal (Florida State University)
[01299] Mathematical modelling of peristaltic driven two-layered catheterized oesophagus
- Session Time & Room : 5D (Aug.25, 15:30-17:10) @D514
- Type : Contributed Talk
- Abstract : An analytical mathematical model for two-layered catheterized oesophagus is presented in the wave-frame. We take due care to conserve the fluids separately. A linear relationship between pressure and flow rate is discovered for catheterized oesophagus. Pressure and flow rate rise in the presence of a catheter with thinner peripheral layer. So it can be suggested that no patient should be fed anything directly through mouth once a catheter has been inserted into the oesophagus.
- Classification : 92C10, 92-10, 35G20, 35G60, 92C35, Biomechanics
- Format : Talk at Waseda University
- Author(s) :
- ANUPAM KUMAR PANDEY (Indian Institute of Technology (BHU), Varanasi)
- Sanjay Kumar Pandey (Indian Institute of Technology (BHU), Varanasi)
[00659] Understanding persisting onchocerciasis hotspots in Africa using mathematical models
- Session Time & Room : 5D (Aug.25, 15:30-17:10) @D514
- Type : Contributed Talk
- Abstract : Onchocerciasis/river blindness is a vector-borne neglected tropical disease with persistent transmission hotspots despite the repeated distribution of ivermectin in endemic communities in Africa. One of the hypotheses for the persistence of transmission is due to the movement of parasites via infected humans and/or vectors between neighbouring communities. I have explored how vector movement affects transmission using spatially-structured mathematical models informed by genetic and environmental data, which might aid in making public-health decisions to eliminate onchocerciasis.
- Classification : 92-08, 92-10, 92D30, 92D25, 92D40
- Format : Talk at Waseda University
- Author(s) :
- Himal Shrestha (La Trobe University)
- Himal Shrestha (La Trobe University)
- Shannon Hedtke (La Trobe University)
- Karen McCulloch (La Trobe University)
- Warwick Grant (La Trobe University)
- Rebecca Chisholm (La Trobe University)
[00709] Mathematical modeling reveals P2X1 purinoceptor antagonist as a male contraceptive
- Session Time & Room : 5D (Aug.25, 15:30-17:10) @D514
- Type : Contributed Talk
- Abstract : Condoms and vasectomies are the only male contraceptive options with disruption of foreplay and reversibility issues. The vas deferens smooth muscle (VDSM) contracts for sperm transportation. The pharmacological inhibition of VDSM contraction might explore promising new contraceptives. We established a mathematical model of VDSM cell using ordinary differential equations for an insilico electrophysiological investigation. The findings from our mathematical model reveal that the P2X1-purinoceptors antagonist 2-phenyl-5,6,7,8- tetrahydroquinoxaline might be considered as a new male contraceptive.
- Classification : 92-08, 92-10, 92-05
- Format : Online Talk on Zoom
- Author(s) :
- CHITARANJAN MAHAPATRA (Paris-Saclay Institute of Neuroscience - CNRS)
- Ashish Kumar Pradhan (Indian Institute of Sciences Bangalore)