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[02695] The position of the axon initial segment assembly site can be predicted from the shape of the neuron

  • Session Time & Room : 3D (Aug.23, 15:30-17:10) @E820
  • Type : Contributed Talk
  • Abstract : A unique compartment called the axon initial segment (AIS) was found critical for the proper development of neuronal polarity. It is unclear how AIS is assembled near the proximal end of the axon during axon specification. In this study, we show that the position of the AIS assembly site is correlated with the zero set of the leading eigenfunction of the Laplace-Beltrami operator solved over the geometry of the neuron. We will then discuss the implications from this observation.
  • Classification : 92C20, 92C15
  • Format : Talk at Waseda University
  • Author(s) :
    • Zhuang Xu (The University of New South Wales)
    • Paul Curmi (University of New South Wales)
    • Christopher Angstmann (University of New South Wales)