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[01333] Development of Dynamical Systems-Inspired Metrics to Evaluate Immunotherapy Efficacy

  • Session Time & Room : 1C (Aug.21, 13:20-15:00) @
  • Type : Industrial Contributed Talk
  • Abstract : Immunotherapy emerged as the new paradigm to treat cancer patients. Computational tools that complement clinical practice are increasingly being used. Standardization of these tools is crucial for their adaptation and widespread implementation. This work contributes in this direction by developing new metrics inspired from dynamical systems and enriching a modular platform that predicts therapeutic issues of combination therapies in immune-oncology, and reduce the burden on clinical trials.
  • Classification : 92C32, 92C42, Quantitative Systems Pharmacology
  • Author(s) :
    • Fahima Nekka (Université de Montréal)
    • Didier Zugaj (Syneos Health)
    • Frédérique Fenneteau (Université de Montréal)
    • Miriam Schirru (Université de Montréal)
    • Hamza Charef (Université de Montréal)
    • Khalil-Elmehdi Ismaili (Université de Montréal)
    • Pierre-Olivier Tremblay (Syneos Health)