Registered Data

[01056] Statistical methodology for functional meta-analysis of sex-based disparities in neurological diseases

  • Session Time & Room : 3E (Aug.23, 17:40-19:20) @E501
  • Type : Industrial Contributed Talk
  • Abstract : Sex-based differences in diverse health scenarios and diseases have been acknowledged for many years but still not thorough-fully analysed. We propose a statistical methodology combining transcriptomics data from different spurces which allows to unveil those disparities at the level of differentially expressed genes and differentially enriched functions. The methodology uses linear models, meta-analysing the results through the logFC, and has been successfully applied to various diseases such as Multiple Sclerosis, Alzheimer’s and Parkinson’s diseases.
  • Classification : 62-xx, 62Pxx, 92-04, 92-08, 92-10
  • Format : Talk at Waseda University
  • Author(s) :
    • Marta R. Hidalgo (CIPF)
    • Francisco Garcia-Garcia (CIPF)
    • Borja Gomez-Cabañes (CIPF)
    • Carla Perpiña-Clerigues (CIPF)
    • Irene Soler-Saez (CIPF)
    • Fernando Gordillo-González (CIPF)
    • Gonzalo Anton-Bernat (Universitat de València)
    • Adolfo López-Cerdan (BioBam )
    • Rubén Grillo-Risco (CIPF)
    • Jose Francisco Català-Senent (INCLIVA)