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[00927] Bone marrow stem cells and exosomes control doxorubicin-induced CRCC: A mathematical model

  • Session Time & Room : 3E (Aug.23, 17:40-19:20) @A601
  • Type : Contributed Talk
  • Abstract : Doxorubicin (DOX), a widely used chemotherapeutic agent, can cause neurodegeneration in the brain, which leads to cancer-related cognitive changes (CRCC). In fact, CRCC is a deteriorating condition which adversely affects the day-to-day life of cancer survivors. Recent studies reported that bone marrow mesenchymal stem cells (BMSCs) and exosome may significantly affect the CRCC conditions in a combination therapy (DOX+Exosome). In this study, we investigate the interaction among intracellular signaling (NFκB-Bcl-2-BAX), DOX, exosome, and IL-6.
  • Classification : 92B05
  • Format : Talk at Waseda University
  • Author(s) :
    • hyungchul Kim (Konkuk University)
    • Donggu Lee (Konkuk University)
    • Haneol Cho (Konkuk university)
    • Junho Lee (Konkuk University)
    • Yangjin Kim (Konkuk University)