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[00762] On the dissolution of particles subject to natural convection

  • Session Time & Room : 3C (Aug.23, 13:20-15:00) @D502
  • Type : Contributed Talk
  • Abstract : The dissolution of a solid spherical particle is a canonical problem that finds many areas of application, including the pharmaceutical industry. In this work, we provide a generalized theory that tackles the role of natural convection in the surrounding dissolving medium. We investigate its effects on hydrodynamics and how it interacts with the diffusion during dissolution to deform the particle geometry whilst altering the release profile of pharmaceutical ingredients, a key aspect in drug delivery.
  • Classification : 76-10, 76R10, 76R50
  • Format : Talk at Waseda University
  • Author(s) :
    • Milton Assunção (University of Limerick)
    • Michael Vynnycky (University of Limerick)
    • Kevin Moroney (University of Limerick)