[00745] Fluid flow and nutrient transport in hollow fibre membrane bioreactors
Session Time & Room : 3C (Aug.23, 13:20-15:00) @A511
Type : Contributed Talk
Abstract : We present an axisymmetric model of fluid flow through a hollow fibre membrane bioreactor for applications in tissue engineering. We derive a reduced model by exploiting the small aspect ratio of bioreactor radius to length. Coupled to a system of reduced-order advection-reaction-diffusion equations for nutrient transport, we reveal how nutrient delivery to cells depends on membrane permeability. We then determine how spatial variations in scaffold permeability can be established to tune nutrient delivery to cells.
