[00667] Effect of tumor-associated neutrophils on tumor growth : A mathematical model
Session Time & Room : 5C (Aug.25, 13:20-15:00) @D515
Type : Contributed Talk
Abstract : Tumor-associated neutrophils (TANs) have been under discussion for their dual role on tumor microenvironment, but they are emerging as important agents in tumor invasion. In this study, we divided TANs into two different phenotypes: N1 TANs, the anti-tumor neutrophils and N2 TANs, the tumorigenic neutrophils. We developed a mathematical model to investigate the dynamics of tumor growth between different TANs and responses to various stimuli, and finally to build simulations for brain tumor treatment.