[00620] Development of an ion channel model-framework
Session Time & Room : 3C (Aug.23, 13:20-15:00) @A511
Type : Contributed Talk
Abstract : Ion channels in cell membranes are of ultimate importance in physiology. They control a large fraction of biological processes and are mainly investigated by current-voltage experiments. To support the interpretation of measured results, we develop a model-framework based on non-equilibrium thermodynamics that accounts for various important aspects, e.g., finite-volume effects and the surface charges of the channel. Julia-based numerical simulations are performed to compute current-voltage relations, with varying ion concentrations, applied voltages, and channel properties.