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[00620] Development of an ion channel model-framework

  • Session Time & Room : 3C (Aug.23, 13:20-15:00) @A511
  • Type : Contributed Talk
  • Abstract : Ion channels in cell membranes are of ultimate importance in physiology. They control a large fraction of biological processes and are mainly investigated by current-voltage experiments. To support the interpretation of measured results, we develop a model-framework based on non-equilibrium thermodynamics that accounts for various important aspects, e.g., finite-volume effects and the surface charges of the channel. Julia-based numerical simulations are performed to compute current-voltage relations, with varying ion concentrations, applied voltages, and channel properties.
  • Classification : 92-10, 92C40, 92-08
  • Format : Talk at Waseda University
  • Author(s) :
    • Christine Keller (Weierstrass Institute for Applied Analysis and Stochastics (WIAS))
    • Juergen Fuhrmann (Weierstrass Institute for Applied Analysis and Stochastics (WIAS))
    • Manuel Landstorfer (Weierstrass Institute for Applied Analysis and Stochastics (WIAS))
    • Barbara Wagner (Weierstrass Institute for Applied Analysis and Stochastics (WIAS))