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[00188] Two-Phase Modelling of Plaque Growth in Early Atherosclerosis

  • Session Time & Room : 3D (Aug.23, 15:30-17:10) @D514
  • Type : Contributed Talk
  • Abstract : We discuss the early stage of atherosclerotic plaque formation within arteries. The production of foam cells characterizes such plaque. Foam cells generate from the differentiated form of monocytes (called macrophages) owing to oxidized low-density lipoprotein (ox-LDL) cholesterol intake. Initially, plaque radius grows exponentially and later on, it stabilizes with time. Such behaviour is due to the death of foam cells owing to the toxicity of excess ox-LDL intake, although ox-LDL enhances foam cell proliferation.
  • Classification : 92C35, 92-10, 76M20, 35B20, 92B05
  • Format : Talk at Waseda University
  • Author(s) :
    • Abdush Salam Pramanik (Department of Mathematics, University of North Bengal)
    • Bibaswan Dey (Department of Mathematics, University of North Bengal)