[00188] Two-Phase Modelling of Plaque Growth in Early Atherosclerosis
Session Time & Room : 3D (Aug.23, 15:30-17:10) @D514
Type : Contributed Talk
Abstract : We discuss the early stage of atherosclerotic plaque formation within arteries. The production of foam cells characterizes such plaque. Foam cells generate from the differentiated form of monocytes (called macrophages) owing to oxidized low-density lipoprotein (ox-LDL) cholesterol intake. Initially, plaque radius grows exponentially and later on, it stabilizes with time. Such behaviour is due to the death of foam cells owing to the toxicity of excess ox-LDL intake, although ox-LDL enhances foam cell proliferation.
